Advances in Chronic Kidney Disease
Volume 11, Issue 2 , Pages 197-201 , April 2004

Hypertension: a disorder of volume control? what is the evidence?

  • Aubrey R Morrison

      Affiliations

    • Department of Medicine, Renal Division, Washington University School of Medicine, St. Louis, MO, USA
    • Corresponding Author InformationAddress correspondence to Aubrey R. Morrison, MD, Department of Medicine, Renal Division, Washington University School of Medicine, Campus Box 8126, St Louis, MO 63110 USA
  • ,
  • Graeme Mindel

      Affiliations

    • Department of Medicine, Renal Division, Washington University School of Medicine, St. Louis, MO, USA

References 

  1. Mosterd A, D’Agostino RBF, Silbershatz H, et al.  Trends in the prevalence of hypertension, antihypertensive therapy, and left ventricular hypertrophy from 1950 to 1989. N Engl J Med. 1999;340:1221–1227
  2. Platt RJ. Heredity in hypertension. Q J Med. 1947;16:111–113
  3. Pickering GW. The genetic factor in essential hypertension. Ann Intern Med. 1955;43:457–464
  4. Karet FE, Lifton RP. Mutations contributing to human blood pressure variation. Recent Prog Hormone Res. 1997;52:263–276
  5. Lifton RP, Gharavi AG, Geller DS. Molecular mechanisms of human hypertension. Cell. 2001;104:545–556
  6. Jeunemaitre X, Charru A, Chatellier G, et al.  M235T variant of the human angiotensinogen gene in unselected hypertensive patients. J Hypertens. 1993;5(suppl):S80–S81
  7. Jeunemaitre X, Soubrier F, Kotelevtsev YV, et al.  Molecular basis of human hypertension (role of angiotensinogen). Cell. 1992;71:169–180
  8. Inoue I, Nakajima T, Williams CS, et al.  A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro. J Clin Invest. 1997;99:1786–1797
  9. Kim H, Krege JH, Kluckman KD, et al.  Genetic control of blood pressure and the angiotensinogen locus. Proc Natl Acad Sci USA. 1995;92:2735–2739
  10. Rich GM, Ulick S, Cook S, et al.  Glucocorticoid-remediable aldosteronism in a large kindred (Clinical spectrum and diagnosis using a characteristic biochemical phenotype). Ann Intern Med. 1992;116:813–820
  11. Lifton RP, Dluhy RG, Powers M, et al.  A chimaeric 11 beta-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension. Nature. 1992;355:262–265
  12. Mune T, Rogerson FM, Nikkila H, et al.  Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase. Nat Genet. 1995;10:394–399
  13. Geller DS, Farhi A, Pinkerton N, et al.  Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy. Science. 2000;289:119–123
  14. Dahl LK, Heine M. Primary role of renal homografts in setting chronic blood pressure levels in rats. Circ Res. 1975;36:692–696
  15. Bianchi G, Baer PG, Fox U, et al.  The role of the kidney in the rat with genetic hypertension. Postgrad Med J. 1977;53(suppl 2):123–138
  16. Curtis JJ, Luke RG, Dustan HP, et al.  Remission of essential hypertension after renal transplantation. N Engl J Med. 1983;309:1009–1015
  17. de Wardener HE, MacGregor GA. The natriuretic hormone and hypertension. Contrib Nephrol. 1980;21:81–87
  18. Levy D, DeStefano AL, Larson MG, et al.  Evidence for a gene influencing blood pressure on chromosome 17 (Genome scan linkage results for longitudinal blood pressure phenotypes in subjects from the Framingham Heart Study). Hypertension. 2000;36:477–483
  19. Law CM, Shiell AW. Is blood pressure inversely related to birth weight? The strength of evidence from a systematic review of the literature. J Hypertens. 1996;14:935–941
  20. Law CM, Martyn CN, Fall CH, et al.  Raised adult blood pressure linked to failure to achieve growth potential in utero. BMJ. 1996;312:1479–1479
  21. Yiu V, Buka S, Zurakowski D, et al.  Relationship between birth weight and blood pressure in childhood. Am J Kidney Dis. 1999;33:253–260
  22. Manning J, Vehaskari VM. Low birth weight-associated adult hypertension in the rat. Pediatr Nephrol. 2001;16:417–422
  23. Manning J, Beutler K, Knepper MA, et al.  Upregulation of renal BSC1 and TSC in prenatally programmed hypertension. Am J Physiol Renal Physiol. 2002;283:F202–F206
  24. Hansson JH, Schild L, Lu Y, et al.  A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity. Proc Natl Acad Sci USA. 1995;92:11495–11499
  25. Hansson JH, Nelson-Williams C, Suzuki H, et al.  Hypertension caused by a truncated epithelial sodium channel gamma subunit (genetic heterogeneity of Liddle syndrome). Nat Genet. 1995;11:76–82
  26. Shimkets RA, Lifton RP, Canessa CM. The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis. J Biol Chem. 1997;272:25537–25541
  27. Henry PC, Kanelis V, O’Brien MC, et al.  Affinity and specificity of interactions between Nedd4 isoforms and the epithelial Na+ channel. J Biol Chem. 2003;278:20019–20028
  28. Schild L, Lu Y, Gautschi I, et al.  Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome. EMBO J. 1996;15:2381–2387
  29. Mansfield TA, Simon DB, Farfel Z, et al.  Multilocus linkage of familial hyperkalaemia and hypertension, pseudohypoaldosteronism type II, to chromosomes 1q31–42 and 17p11-q21. Nat Genet. 1997;16:202–205
  30. Disse-Nicodeme S, Achard JM, Potier J, et al.  Familial hyperkalemic hypertension (Gordon syndrome) (Evidence for phenotypic variability in a study of 7 families). Adv Nephrol Necker Hosp. 2001;31:55–68
  31. Wilson FH, Disse-Nicodeme S, Choate KA, et al.  Human hypertension caused by mutations in WNK kinases. Science. 2001;293:1107–1112
  32. Guyton AC. Kidneys and fluids in pressure regulation (Small volume but large pressure changes). Hypertension. 1992;19(suppl 1):I2–I8
  33. Guyton AC. Blood pressure control—special role of the kidneys and body fluids. Science. 1991;252:1813–1816

PII: S1073-4449(04)00007-X

doi: 10.1053/j.arrt.2004.01.006

Advances in Chronic Kidney Disease
Volume 11, Issue 2 , Pages 197-201 , April 2004