Advances in Chronic Kidney Disease
Volume 11, Issue 2 , Pages 184-191, April 2004

Cardiovascular risk reduction and preservation of renal function in the early nephropathy patient

  • Peter A McCullough

      Affiliations

    • Department of Medicine, Divisions of Cardiology, Nutrition, and Preventive Medicine, William Beaumont Hospital, Royal Oak, MI, USA
    • Corresponding Author InformationAddress correspondence to Peter A. McCullough, MD, MPH, Division of Clinical Nutrition and Preventive Medicine, William Beaumont Hospital, 4949 Coolidge Highway, Royal Oak, MI 48073 USA

Abstract 

The obesity pandemic is driving secondary epidemics of type II diabetes and hypertension, resulting in rising rates of patients with early nephropathy at risk for cardiovascular disease. Estimation of glomerular filtration rate and assessment of microalbuminuria are key screening measures for this patient population. Combined with reduction of traditional cardiovascular risk factors, reducing the rate of progression of chronic kidney disease is expected to have an additive beneficial effect in this population. This article reviews a common strategy for prevention of both cardiac and kidney endpoints in patients with early nephropathy.

Keywords:  Cardiovascular disease, chronic kidney disease, atherosclerosis, microalbuminuria, hypertension, nephropathy, diabetes

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PII: S1073-4449(04)00010-X

doi:10.1053/j.arrt.2004.01.009

Advances in Chronic Kidney Disease
Volume 11, Issue 2 , Pages 184-191, April 2004