Advances in Chronic Kidney Disease
Volume 11, Issue 3 , Pages 294-303, July 2004

Opportunities for improvement in the cardiovascular care of patients with end-stage renal disease

  • Peter A McCullough

      Affiliations

    • Department of Medicine, Divisions of Cardiology, Nutrition, and Preventive Medicine, William Beaumont Hospital, Royal Oak, MI, USA
    • Corresponding Author InformationAddress correspondence to Peter A. McCullough, MD, MPH, Division of Clinical Nutrition and Preventive Medicine, William Beaumont Hospital, 4949 Coolidge Highway, Royal Oak, MI 48073 USA

Abstract 

Cardiovascular disease accounts for the majority of morbidity and mortality in patients with end-stage renal disease (ESRD). Studies have identified several explanations for this observation, such as high rates of cardiovascular risk factors, lesser use of cardioprotective strategies, adverse outcomes with cardiovascular drugs and procedures, and accelerated atherosclerosis and myocardial disease in ESRD. Based on these findings, this article addresses the critical opportunities for improvement in cardiovascular outcomes in patients with ESRD. These improvements include prevention of cardiovascular events, management of acute coronary syndromes and heart failure, and the prevention of sudden death.

Keywords:  Cardiovascular disease, end-stage renal disease, atherosclerosis, acute coronary syndromes, heart failure, sudden death

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PII: S1548-5595(04)00078-3

doi:10.1053/j.arrt.2004.04.009

Advances in Chronic Kidney Disease
Volume 11, Issue 3 , Pages 294-303, July 2004