Advances in Chronic Kidney Disease
Volume 12, Issue 3 , Pages 261-275 , July 2005

Kidney Injury From Alternative Medicines

  • Conny R.D. Colson
  • ,
  • Marc E. De Broe

      Affiliations

    • Corresponding Author InformationAddress correspondence to Marc E. De Broe, MD, PhD, Department of Nephrology-Hypertension, University of Antwerp (Campus Drie Eiken), p/a Antwerp University Hospital, Wilrijkstraat 10, B-2650 Edegem/Antwerpen, Belgium.

References 

  1. Traditional medicine. Available at: http://www.who.int/mediacentre/factsheets/fs134/en. Accessed January 15, 2005
  2. Dahl NV . Herbs and supplements in dialysis patients (Panacea or poison?) . Semin Dial . 2001;14:186–192
  3. Jha V , Chugh KS . Nephropathy associated with animal, plant and chemical toxines in the tropics . Semin Nephrol . 2003;23:49–65
  4. Roemheld-Hamm B , Dahl NV . Herbs, menopause, and dialysis . Semin Dial . 2002;15:53–59
  5. Bagnis CI , Deray G , Baumelou A , et al.   Herbs and the kidney . Am J Kidney Dis . 2004;44:1–11
  6. Marcus DM , Grollman AP . Botanical medicines—The need for new regulations . N Engl J Med . 2002;347:2073–2076
  7. Huxtable RJ . The harmful potential of herbal and other plant products . Drug Safety . 1990;5(suppl 1):126–136
  8. Tomlinson B , Chan TYK , Chan JCN , et al.   Toxicity of complementary therapies (An Eastern perspective) . J Clin Pharmacol . 2000;40:451–456
  9. De Smet PAGM . Herbal remedies . N Engl J Med . 2002;347:2046–2056
  10. Seedat YK . Acute renal failure among blacks and Indians in South Africa . S Afr Med J . 1978;54:427–431
  11. Adelkum TA , Ekwere TR , Akinsola A . The pattern of acute toxic nephropathy in Ife, Nigeria . West Afr J Med . 1999;18:60–63
  12. Ojogwu LI , Anah C . Renal failure and hypertension in tropical Africa—A pre-dialysis experience from Nigeria . East Afr Med J . 1983;60:478–484
  13. Randeree IG , Czarnocki A , Moodley J , et al.   Acute renal failure in pregnancy I South Africa . Renal Failure . 1995;17:147–153
  14. Kadiri S , Ogunlesi A , Osinfade K , et al.   The causes and course of acute tubular necrosis in Nigerians . Afr J Med Sci . 1992;21:91–96
  15. Gold CH . Acute renal failure from herbal and patent remedies in blacks . Clin Nephrol . 1980;14:28–34
  16. Dukes DC , Dukes HM , Gordon JA , et al.   Acute renal failure in Central Africa. The toxic effects of traditional African medicine . Centr Afr J Med . 1969;15:71–78
  17. Otieno LS , McLigeyo SO , Luta M . Acute renal failure following the use of herbal remedies . East Afr Med J . 1991;68:993–998
  18. Seedat YK . Acute renal failure in the black population of South Africa . Int J Artif Organs . 1993;16:801–802
  19. Lowenthal MN , Jones IG , Mohelsky V . Acute renal failure in Zambian women using traditional herbal remedies . J Trop Med Hyg . 1974;77:190–192
  20. Nyazema NZ . Poisoning due to traditional remedies . Centr Afr J Med . 1984;30:80–83
  21. Larry D . Hepatoxicity of herbal remedies . J Hepatol . 1997;26:47–51
  22. Swanepoel C , Naicker S , Moosa R , et al.   Nephrotoxins in Africa . In:  De Broe ME ,  Porter GA ,  Bennett WM , et al. editor. Clinical Nephrotoxins . (ed 2). The Netherlands: Kluwer Academic Publishers; 2003;p. 603–611
  23. De Broe ME . Acute renal failure and toxic nephropathies . In:  El-Nahas M ,  Barsoum R ,  Dirks J , et al. editor. Kidney Diseases in Ethnic Minorities and the Developing World . New York, NY: Marcel Dekker Inc; 2005; (in press)
  24. Watson AR , Coodivia HM , Bhoola KD . The clinical syndrome of Impilla (Callilepsis laureola) poisoning in children . S Afr Med J . 1979;55:290–292
  25. Wainwright J , Schonland MM , Candy HA . Toxicity of Callilepsis laureola . S Afr Med J . 1977;52:313–315
  26. Seedat YK , Hitchcock PJ . Acute renal failure from callilepsis laureola . S Afr Med J . 1971;45:832–833
  27. Popat A , Shear NH , Malkiewicz I , et al.   The toxicity of Callipepsis laureola, a South African traditional medicine . Clin Biochem . 2001;34:229–236
  28. Zoratti M , Szabo I . The mitochondrial permeability transition . Biochem Biophys Acta . 1995;1241:139–176
  29. Vancompernolle K , Van Herreweghe F , Pynaert G , et al.   Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity . FEBS Lett . 1998;438:150–158
  30. Nogue S , Sanz P , Botey A , et al.   Insuffisance rénale aiguë due a une intoxication par le charbon à glu (Atractylis gummifera-L) . Presse Med . 1992;21:130
  31. Luyckx VA , Ballantine R , Claeys M , et al.   Herbal remedy-associated acute renal failure secondary to Cape aloes . Am J Kidney Dis . 2002;39:1–5
  32. In:  Nuewinger HD editors. Afrikanische Arzneiflanzen und Jagdgifte . Stutgart: Wissenschaftliche Verlaggesellschaft mbH; 1994;p. 489–494
  33. Hilepo JN , Belluci AG , Mossey RT . Acute renal failure caused by “cat’s claw” herbal remedy in a patient with systemic lupus erythematosus . Nephron . 1997;77:361
  34. Arseculeratne SN , Gunatilaka AAL , Panabokke RG . Studies on medicinal plants of Sri Lanka, part 14 (Toxicity of some traditional medicinal herbs) . J Ethnopharmacol . 1985;13:323–335
  35. Sakuja YK , Sud K . Acute renal failure in the tropics . Saudi J Kidney Dis Tansplant . 1998;9:247–260
  36. Lin YF , Lin SH . Simultaneous acute renal and hepatic failure after ingesting raw carp gall bladder . Nephrol Dial Transplant . 1999;14:2011–2012
  37. Sahoo RN , Mohapatra MK , Sahoo B , et al.   Acute renal failure associated with freshwater fish toxin . Trop Geograph Med . 1995;47:94–95
  38. Park SK , Kim DG , Kang SK , et al.   toxic acute renal failure and hepatitis after ingestion of raw carp bile . Nephron . 1990;56:188–193
  39. Choi K , Park SW , Lee KJ , et al.   Grass carp (Ctenopharyngodon idellus) bile may inhibit the release of renal dipeptidase from the proximal tubules by nitric oxide generation . Kidney Blood Press Res . 2000;23:113–118
  40. Hepatic and renal toxicity among patients ingesting sheep bile as an unconventional remedy for diabetes mellitus—Saudi Arabia, 1995 . MMWR Morb Mortal Wkly Rep . 1996;45:941–943
  41. Lin JL , Ho YS . Flavanoid-induced acute nephropathy . Am J Kidney Dis . 1994;23:433–440
  42. Jaeger A , Walti M , Neftel K . Side effects of flavanoids in medical practice . Prog Clin Biol Res . 1988;280:379–394
  43. Molhuysen JA , Gerbrandy J , De Vries LA , et al.   A liquorice extract with deoxycortone-like action . Lancet . 1950;2:381–386
  44. Stewart PM , Wallace AM , Valentine R , et al.   Mineralocorticoid activity of liquorice (11β-hydroxysteroid dehydrogenase deficiency comes of age) . Lancet . 1987;2:821–824
  45. Funder JW , Pearce PT , Smith R , et al.   Mineralocorticoid action (target tissue specificity is enzyme, not receptor mediated) . Science . 1988;243:583–585
  46. Delcroix C , Poncin E , Pourrat O , et al.   Proximal tubulopathy in licorice poisoning . Presse Med . 1985;14:2346–2347
  47. De Klerk GJ , Nieuwenhuis MG , Beutler J . Lesson of the week (Hypokalaemia and hypertension associated with the use of liquorice flavored chewing gum) . BMJ . 1997;314:731–735
  48. Walker BR , Edwards CRW . Licorice-induced hypertension and syndromes of apparent mineralocorticoid excess . Endocrinol Metab Clin North Am . 1994;23:359–377
  49. Winslow LC , Kroll DJ . Herbs as medicines . Arch Intern Med . 1998;158:2192–2199
  50. Tomlinson B , Chan TY , Chan JC , et al.   Toxicity of complementary therapies (an Eastern perspective) . J Clin Pharmacol . 2000;40:451–456
  51. Izumotani T , Ishimura E , Tsumura K , et al.   An adult case of Fanconi syndrome due to a mixture of Chinese crude drugs . Nephron . 1993;65:137–140
  52. The Review of Natural Products . St Louis, MO: Facts and Comparisons; 1997;
  53. US Food and Drug Administration. Illnesses and injuries associated with the use of selected dietary supplements. Unsubstanciated claims and documented health hazards in the dietary supplement marketplace. Available at: www.cfsan.fda.gov/∼dms/ds-ill.htm. Accessed January 15, 2005
  54. Powell T , Hsu F , Turk J , et al.   Ma-huang strikes again (Ephedrine nephrolithiasis) . Am J Kidney Dis . 1998;32:153–159
  55. Haller C , Benowitz N . Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids . N Engl J Med . 2000;343:1833–1838
  56. Djibo A , Bouzou SB . Intoxication aiguë au “sobi-lobi” (Datura). A propos de quatre cas au Niger . Bull Soc Pathol Exot . 2000;93:294–297
  57. Chan JCN , Chan TYK , Chan KL , et al.   Anticholinergic poisoning from Chinese herbal medicines . Aust N Z J Med . 1994;24:317–318
  58. Harkins KJ . What’s the use of cranberry juice? . Age Ageing . 2000;29:9–12
  59. Bodel PT , Cotran R , Kass E . Cranberry juice and the antibacterial action of hippuric acid . J Lab Clin Med . 1959;54:881–888
  60. Jackson MS , Hicks L . Effect of cranberry juice on urinary pH in older adults . Home Health Nurs . 1997;15:199–202
  61. Zafiri D , Ofek I , Adar R , et al.   Inhibitory activity of cranberry juice on adherence of type I and type P fimbriated Escherichia coli to eukaryotic cells . Antimicrob Agents Chemother . 1989;33:92–98
  62. Ofek I , Goldhar J , Zafiri D , et al.   Anti-Escherichia coli adhesin activity of cranberry and blueberry juices . N Engl J Med . 1991;324:1599
  63. Jepson RG , Mihaljevic L , Craig J . Cranberries for preventing urinary tract infection (Cochrane Review) . Cochrane Database Syst Rev . 2004;1:CD001321
  64. Van Der Spoel JI , Stricker BHC , Schipper MEI , et al.   Toxische beschadiging van nier, lever en spier toegeschreven aan het gebruik van germanium-lactaat-citraat . Ned Tijdschr Geneeskd . 1991;135:1134–1137
  65. Hainer MI , Tsai N , Komura ST , et al.   Fatal hepatorenal failure associated with hydrazine sulfate . Ann Int Med . 2000;133:877–880
  66. Sotaniemi E , Hirovonen J , Isomaki H , et al.   Hydrazine toxicity in the human. Report of a fatal case . Ann Clin Res . 1971;3:30–33
  67. Akdogan M , Kilinç I , Oncu M , et al.   Investigation of biochemical and histopathological effects of Mentha piperata L. and Mentha spicata L. on kidney tissue in rats . Hum Exp Toxicol . 2003;22:213–219
  68. Till JS , Majmudar BN . Cantharidin poisoning . South Med J . 1982;74:444–447
  69. Karras DJ , Farrell SE , Harrigan RA , et al.   Poisoning from “Spanish fly” (cantharidin) . Am J Emerg Med . 1996;14:478–483
  70. In: WHO Cadmium (Environmental Health Criteria) . Geneva: WHO; 1992;p. 280
  71. Friberg L . Cadmium and health (A toxicological and epidemiologic appraisal) . In:  Friberg L ,  Elinder CG ,  Kjellström T , et al. editor. Cadmium and Health (A Toxicological and Epidemiologic Appraisal) . vol 2: Boca Raton, FL: CRC Press; 1986;
  72. Van Vleet TR , Schnellmann RG . Toxic nephropathy (Environmental chemicals) . Semin Nephrol . 2003;23:500–508
  73. Friberg L . Health hazards in the manufacture of alkaline accumulators with special reference to chronic cadmium poisoning . Acta Med Scand . 1950;240(suppl):1–124
  74. Järup L , Elinder CG . Incidence of renal stones among cadmium exposed battery workers . Br J Ind Med . 1993;50:598–602
  75. Mueller PW , Smith SJ , Steinberg KK , et al.   Chronic renal tubular effects in relation to urine cadmium levels . Nephron . 1989;52:45–54
  76. Kanzantzis G . Renal tubular dysfunction and abnormalities of cadmium metabolism in cadmium workers . Environ Health Perspect . 1979;28:155–159
  77. Atherton DJ , Rustin MH , Brostoff J . Need for correct identification of herbs in herbal poisoning . Lancet . 1993;341:637–638
  78. Wu MS , Hong JJ , Lin CW , et al.   Multiple tubular dysfunction induced by mixed Chinese herbal medicines containing cadmium . Nephrol Dial Transplant . 1996;11:867–870
  79. S̆ubat-Dez̆ulović M , Slavić I , Roz̆manić V , et al.   Drug-induced acute tubulointerstitial nephritis (A case with elevated urinary cadmium) . Pediatr Nephrol . 2002;17:382–385
  80. Cunha J , Pereira L , Pun MI , et al.   Arsenic and acute lethal intoxication . Hong Kong Pharm J . 1998;7:50–53
  81. Espinoza EO , Mann MJ , Blaesdell B . Arsenic and mercury in traditional Chinese herbal balls . N Engl J Med . 1995;333:803–804 (letter)
  82. Wood R , Mills PB , Knobel GJ , et al.   Acute dichromate poisoning after use of traditional purgatives . S Afr Med J . 1990;77:640–642
  83. Geraghty M . Herbal supplements for renal patients (What do we know?) . Nephrol News Issues . 2000;14:12–13 42–43, 54
  84. Diamond J , Pallone T . Acute interstitial nephritis following use of Tung Shueh pills . Am J Kidney Dis . 1994;24:219–221
  85. Segasothy M , Samad S . Illicit herbal preparation containing phenylbutazone causing analgesic nephropathy . Nephron . 1991;59:166–167
  86. Hamdouk MI , Suleiman SM , Kallel H , et al.   Paraphenylene diamine hair dye poisoning . In:  De Broe ME ,  Porter GA ,  Bennett WM ,  Verpooten GA editor. Clinical Nephrotoxins—Renal Injury from Drugs and Chemicals . (2nd edition). Dordrecht: Kluwer Academic Publishers; 2003;p. 611–618
  87. Sir Hashim M , Hamza YO , Yahia B , et al.   Poisoning from henna dye and para-phenylenediamine mixtures in children in Khartoum . Ann Trop Paediatr . 1992;12:3–6
  88. Bourquia A , Jabrane AJ , Ramdani B , et al.   Systemic toxicity of paraphenylenediamine (4 cases) . Presse Med . 1998;17:1798–1800
  89. Averbukh Z , Modai D , Leonov Y , et al.   Rhabdomyolysis and acute renal failure induced by paraphenylenediamine . Hum Toxicol . 1989;8:345–348
  90. Shemesh IY , Mishal Y , Baruchin AM , et al.   Rhabdomyolysis in paraphenylenediamine intoxication . Vet Hum Toxicol . 1995;37:244–245
  91. Saito K , Murai T , Yabe K , et al.   [Rhabdomyolysis due to paraphenylenediamine (hair dye)—Report of an autopsy case] . Nippon Hoigaku Zasshi . 1990;44:469–474
  92. Nott HW . Systemic poisoning by hair dye . Br Med J . 1924;1:421–422
  93. Mathur AK , Gupta BN , Narang S , et al.   Biochemical and histopathological changes following dermal exposure to paraphenylene diamine in guinea pigs . J Appl Toxicol . 1990;10:383–386
  94. Hamdouk M . PPD nephrotoxicity, in paraphenylene diamine (hair dye) acute systemic toxicity . Sheffield, UK: Sheffield Kidney Institute; 2001; (thesis)
  95. Prakash J . Acute renal failure in epidemic dropsy . Renal Failure . 1999;21:707–711
  96. Pasricha CL , Lal S , Malik KS , et al.   An outbreak of epidemic dropsy in a close community . Ind Med Gaz . 1939;74:133–136
  97. Bhende YM . Vascular changes produced by Argemone oil II-changes in rats given injection of the oil . J Post Grad Med . 1956;2:185
  98. Sood NN , Sachdev MS , Mohan M , et al.   Epidemic dropsy following transcutaneous absorption of Argemone mexicana oil . Trans R Soc Med Hyg . 1985;79:510–512
  99. Vanherweghem JL , Depierreux M , Tielemans C , et al.   Rapidly progressive interstitial renal fibrosis in young women (Association with slimming regimen including Chinese herbs) . Lancet . 1993;341:387–391
  100. Depierreux M , Van Damme B , Vanden Houte K , et al.   Pathologic aspects of a newly described nephropathy related to the prolonged use of Chinese herbs . Am J Kidney Dis . 1994;24:172–180
  101. Vanhaelen M , Vanhaelen-Fastre R , But P , et al.   Identification of aristolochic acid in Chinese herbs . Lancet . 1994;343:174
  102. Vanherweghem JL . Misuse of herbal remedies (The case of an outbreak of terminal renal failure in Belgium (Chinese herbs nephropathy)) . J Altern Complement Med . 1998;4:9–13
  103. Cosyns JP , Dehoux JP , Guiot Y , et al.   Chronic aristolochic acid toxicity in rabbits (A model of Chinese herbs nephropathy?) . Kidney Int . 2001;59:2164–2173
  104. Debelle FD , Nortier JL , De Prez EG , et al.   Aristolochic acids induce chronic renal failure with interstitial fibrosis in salt-depleted rats . J Am Soc Nephrol . 2002;13:431–436
  105. De Broe ME . On a nephrotoxic and carcinogenic slimming regimen . Am J Kidney Dis . 1999;33:1171–1173
  106. Tanaka A , Nishida R , Yoshida T , et al.   Outbreak of Chinese herb nephropathy in Japan (Are there any differences from Belgium?) . Intern Med . 2001;40:296–300
  107. Ng YY , Yu S , Chen TW , et al.   Interstitial renal fibrosis in a young woman (Association with a Chinese preparation given for irregular menses) . Nephrol Dial Transplant . 1998;13:2115–2117
  108. Farrell J , Campbell E , Walshe JJ . Renal failure associated with alternative medical therapies . Renal Failure . 1995;17:759–764
  109. Woelk H . Comparison of St John’s wort and imipramine for treating depression (Randomized controlled trial) . BMJ . 2000;321:536–539
  110. Ernst E . The risk-benefit profile of commonly used herbal therapies (Ginkgo, St John’s wort, ginseng, echinacea, saw palmetto, and kava) . Ann Intern Med . 2002;136:42–53
  111. Ernst E . Second thoughts about safety of St John’s wort . Lancet . 1999;354:2014–2016
  112. Johne A , Brockmoller J , Bauer S , et al.   Pharmacokinetic interaction of digoxin with an herbal extract from St John’s wort (Hypericum perforatum) . Clin Pharmacol Ther . 1999;66:338–345
  113. Piscitelli SC , Burstein AH , Chaitt D , et al.   Indinavir concentrations and St John’s wort . Lancet . 2000;355:547–548
  114. Yue QY , Bergquist C , Gerden B . Safety of St John’s wort (Hypericum perforatum) . Lancet . 2000;355:576–577
  115. Nebel A , Schneider BJ , Baker RK , et al.   Potential metabolic interaction between St. John’s wort and theophylline . Ann Pharmacother . 1999;33:502
  116. Bolley R , Zulke C , Kammerl M , et al.   Tacrolimus-induced nephrotoxicity unmasked by induction of the CYP3A4 system with St John’s wort . Transplantation . 2002;73:1009
  117. Barone GW , Gurley BJ , Ketel BL , et al.   Herbal supplements (A potential for drug interactions in transplant recipients) . Transplantation . 2001;71:239–241
  118. Moshella C , Jaber BL . Interaction between cyclosporine and Hypericum perforatum (St John’s wort) after organ transplantation . Am J Kidney Dis . 2001;38:1105–1107
  119. Breidenbach T , Hoffmann MW , Becker T , et al.   Drug interaction of St John’s wort with cyclosporin . Lancet . 2000;355:1912; (letter)
  120. Mai I , Strömer E , Bauer S , et al.   Impact of St John’s wort treatment on the pharmacokinetics of tacrolimus and mycophenolic acid in renal transplant patients . Nephrol Dial Transplant . 2003;18:819–822
  121. Breidenbach T , Kliem V , Burg M , et al.   Profound drop of cyclosporin A whole blood trough levels caused by St John’s wort (Hypericum perforatum) . Transplantation . 2000;69:2229–2230 (letter)
  122. Durr D , Stieger B , Kullak-Ublick GA , et al.   St John’s wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP 3A4 . Clin Pharmacol Ther . 2000;68:598–604
  123. Moore LB , Goodwin B , Jones SA , et al.   St. John’s wort induces hepatic drug metabolism through activation of the pregnane x receptor . Proc Natl Acad Sci U S A . 2000;97:7500–7502
  124. Light TD , Light JA . Acute renal transplant rejection possibly related to herbal medications . Am J Transplant . 2003;3:1608–1609

PII: S1548-5595(05)00072-8

doi: 10.1016/j.ackd.2005.03.006

Advances in Chronic Kidney Disease
Volume 12, Issue 3 , Pages 261-275 , July 2005