The renal regulation of phosphate is a complex process. Clinical disorders of phosphate handling have led to the identification of several genes and proteins involved in the maintenance of phosphate homeostasis. Further work is required to elucidate the precise pathways that regulate renal phosphate transport.
aDepartments of Medicine, Physiology and Biophysics, Division of Renal Diseases and Hypertension, University of Colorado Health Sciences Center, Denver, CO
bDepartment of Toxicology, University of Zaragoza, Zaragoza, Spain.
Address correspondence to Moshe Levi, MD, Departments of Medicine, Physiology and Biophysics, Division of Renal Diseases and Hypertension, University of Colorado Health Sciences Center, 4200 East 9th Avenue, Denver, CO 80262.