« Previous
Next »
Advances in Chronic Kidney Disease
Volume 16, Issue 6
, Pages 420-429
, November 2009
The Intersection of Geriatrics and Chronic Kidney Disease: Frailty and Disability Among Older Adults With Kidney Disease
References
- Prevalence of chronic kidney disease in the United States. JAMA. 2007;298:2038–2047
- Octogenarians and nonagenarians starting dialysis in the United States. Ann Intern Med. 2007;146:177–183
- Changes in survival among elderly patients initiating dialysis from 1990 to 1999. Can Med Assoc J. 2007;177:1033–1038
- Cystatin C and aging success. Arch Intern Med. 2008;168:147–153
- Predictive value of functional status for mortality in patients on maintenance hemodialysis. Am J Nephrol. 1998;18:109–116
- . An analysis of the increased demands placed on dialysis health care team members by functionally dependent hemodialysis patients. Am J Kidney Dis. 2000;35:1061–1067
- . USRDS 2008 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 2008;
- . Incidence, prevalence, and outcomes of end-stage renal disease patients placed in nursing homes. Am J Kidney Dis. 1993;21:619–627
- . A conceptual framework of frailty: A review. J Gerontol A Biol Sci Med Sci. 2002;57:M283–M288
- Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: A consensus report. J Am Geriatr Soc. 2004;52:625–634
- Untangling the concepts of disability, frailty, and comorbidity: Implications for improved targeting and care. J Gerontol A Biol Sci Med Sci. 2004;59:255–263
- From bedside to bench: Research agenda for frailty. Sci Aging Knowledge Environ. 2005;2005:pe24
- . Dynamics of stability: The physiologic basis of functional health and frailty. J Gerontol A Biol Sci Med Sci. 2002;57:B115–B125
- Frailty in older adults: Evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56:M146–M156
- Transitions between frailty states among community-living older persons. Arch Intern Med. 2006;166:418–423
- Frailty: Emergence and consequences in women aged 65 and older in the Women's Health Initiative Observational Study. J Am Geriatr Soc. 2005;53:1321–1330
- Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older women. Arch Intern Med. 2008;168:382–389
- A comparison of frailty indexes for the prediction of falls, disability, fractures, and mortality in older men. J Am Geriatr Soc. 2009;57:492–498
- Hospitalization, restricted activity, and the development of disability among older persons. JAMA. 2004;292:2115–2124
- The development of insidious disability in activities of daily living among community-living older persons. Am J Med. 2004;117:484–491
- Cognitive impairment improves the predictive validity of the phenotype of frailty for adverse health outcomes: the three-city study. J Am Geriatr Soc. 2009;57:453–461
- Long-term risks of death and institutionalization of elderly people in relation to deficit accumulation at age 70. J Am Geriatr Soc. 2006;54:975–979
- Geriatric syndromes: Clinical, research, and policy implications of a core geriatric concept. J Am Geriatr Soc. 2007;55:780–791
- Shared risk factors for falls, incontinence, and functional dependence. Unifying the approach to geriatric syndromes. JAMA. 1995;273:1348–1353
- Change in cardiovascular risk factors with progression of kidney disease. Am J Nephrol. 2009;29:334–341
- Level of kidney function as a risk factor for cardiovascular outcomes in the elderly. Kidney Int. 2003;63:1121–1129
- The presence of frailty in elderly persons with chronic renal insufficiency. Am J Kidney Dis. 2004;43:861–867
- Adipose endocrine function, insulin-like growth factor-1 axis, and exceptional survival beyond 100 years of age. J Gerontol A Biol Sci Med Sci. 2008;63:1209–1218
- . Anemia and the frail elderly. Semin Hematol. 2008;45:261–266
- Characterization of frailty in older adults with chronic kidney disease (CKD): Correlations with biomarkers of inflammation. J Am Soc Nephrol. 2005;16:514a
- Significance of frailty among dialysis patients. J Am Soc Nephrol. 2007;18:2960–2967
- . Difficulty and dependence: Two components of the disability continuum among community-living older persons. Ann Intern Med. 1998;128:96–101
- . Assessing risk for the onset of functional dependence among older adults: The role of physical performance. J Am Geriatr Soc. 1995;43:603–609
- Dismal rehabilitation in predominantly type II diabetics on dialysis in inner-city Brooklyn. Clin Nephrol. 2000;54:94–104
- . Physical activity and employment status of patients on maintenance dialysis. N Engl J Med. 1981;304:309–313
- . Demographics, diabetes type, and degree of rehabilitation in diabetic patients on maintenance hemodialysis in Brooklyn. J Diabet Complications. 1988;2:218–226
- Independence in activities of daily living for end-stage renal disease patients: Biomedical and demographic correlates. Am J Kidney Dis. 1989;13:61–69
- . Assisted survival, aging, and rehabilitation needs: Comparison of older dialysis patients and age-matched peers. Arch Phys Med Rehabil. 1992;73:309–315
- . Hemodialysis patient-assessed functional health status predicts continued survival, hospitalization, and dialysis-attendance compliance. Am J Kidney Dis. 1997;30:204–212
- Pervasive failed rehabilitation in center-based maintenance hemodialysis patients. Am J Kidney Dis. 1994;23:394–400
- Dismal rehabilitation in geriatric inner-city hemodialysis patients. JAMA. 1994;271:29–33
- Relationship between conditions addressed by hemodialysis guidelines and non-ESRD-specific conditions affecting quality of life. Clin J Am Soc Nephrol. 2009;4:572–578
- . Functional dependencies among the elderly on hemodialysis. Kidney Int. 2008;73:1289–1295
- . The timed “Up & Go”: A test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991;39:142–148
- The dynamic nature of mobility disability in older persons. J Am Geriatr Soc. 2006;54:248–254
- Transitions between states of disability and independence among older persons. Am J Epidemiol. 2005;161:575–584
- . A prospective pilot study to measure changes in functional status associated with hospitalization in elderly dialysis-dependent patients. Am J Kidney Dis. 2008;52:956–961
- Association of kidney function with incident hip fracture in older adults. J Am Soc Nephrol. 2007;18:282–286
- . An age-related decrease in creatinine clearance is associated with an increase in number of falls in untreated women but not in women receiving calcitriol treatment. J Clin Endocrinol Metab. 2007;92:51–58
- . Falls are associated with decreased renal function and insufficient calcitriol production by the kidney. J Steroid Biochem Mol Biol. 2007;103:610–613
- A new significant and independent risk factor for falls in elderly men and women: A low creatinine clearance of less than 65 ml/min. Osteoporos Int. 2005;16:332–338
- Falls and fall-related injuries in older dialysis patients. Clin J Am Soc Nephrol. 2006;1:1191–1196
- Falls in hemodialysis patients: Prospective study of incidence, risk factors, and complications. Am J Kidney Dis. 2005;45:148–153
- Prevention of fall-related injuries in long-term care: A randomized controlled trial of staff education. Arch Intern Med. 2005;165:2293–2298
- Geriatric comorbidities, such as falls, confer an independent mortality risk to elderly dialysis patients. Nephrol Dial Transplant. 2008;23:1396–1400
- Chronic kidney disease, creatinine and cognitive functioning. Nephrol Dial Transplant. 2009;24:2446–2452
- Chronic kidney disease and cognitive impairment in the elderly: The health, aging, and body composition study. J Am Soc Nephrol. 2005;16:2127–2133
- Kidney function and cognitive impairment in US adults: The Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Am J Kidney Dis. 2008;52:227–234
- Cognitive impairment in hemodialysis patients is common. Neurology. 2006;67:216–223
- Correlates and outcomes of dementia among dialysis patients: The Dialysis Outcomes and Practice Patterns Study. Nephrol Dial Transplant. 2006;21:2543–2548
- Dementia as a predictor of mortality in dialysis patients. Clin J Am Soc Nephrol. 2006;1:1000–1005
- The regional cerebral blood flow in patients under chronic hemodialytic treatment. J Cereb Blood Flow Metab. 1987;7:659–661
- Effects of hemodialysis on cerebral circulation evaluated by transcranial Doppler ultrasonography. Stroke. 1994;25:408–412
- Hemodialysis causes severe orthostatic reduction in cerebral blood flow velocity in diabetic patients. Am J Kidney Dis. 1999;34:1096–1104
- . Dialysis disequilibrium syndrome: Current concepts on pathogenesis and prevention. Kidney Int. 1994;45:629–635
- Acute variation in cognitive function in hemodialysis patients: A cohort study with repeated measures. Am J Kidney Dis. 2007;50:270–278
- Pretransplant physical functioning and kidney patients' risk for posttransplantation hospitalization/death: Evidence from a national cohort. Clin J Am Soc Nephrol. 2006;1:837–843
- A short physical performance battery assessing lower extremity function: Association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol. 1994;49:M85–M94
- Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. N Engl J Med. 1995;332:556–561
- A program to prevent functional decline in physically frail, elderly persons who live at home. N Engl J Med. 2002;347:1068–1074
- A prehabilitation program for the prevention of functional decline: Effect on higher-level physical function. Arch Phys Med Rehabil. 2004;85:1043–1049
- Preventing injuries in older people by preventing falls: A meta-analysis of individual-level data. J Am Geriatr Soc. 2002;50:905–911
- . The end of the disease era. Am J Med. 2004;116:179–185
- Association between multidisciplinary care and survival for elderly patients with chronic kidney disease. J Am Soc Nephrol. 2007;18:993–999
- . Medical management of frailty: Confessions of a gnostic. Can Med Assoc J. 1997;157:1081–1084
- Responsiveness of goal attainment scaling in a randomized controlled trial of comprehensive geriatric assessment. J Clin Epidemiol. 2003;56:736–743
Supported by St. Paul's Hospital Foundation Physician Scholar Award.
PII: S1548-5595(09)00132-3
doi: 10.1053/j.ackd.2009.07.008
© 2009 National Kidney Foundation, Inc. Published by Elsevier Inc All rights reserved.
« Previous
Next »
Advances in Chronic Kidney Disease
Volume 16, Issue 6
, Pages 420-429
, November 2009
