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Poisoning, Toxicology, and the Nephrologist

      In 2017, the American Association of Poison Control Centers reported more than 2.1 million human toxic exposures across the United States. In fact, toxic exposures with serious outcomes have increased every year since 2000.
      • Gummin D.D.
      • Mowry J.B.
      • Spyker D.A.
      • Brooks D.E.
      • Osterthaler K.M.
      • Banner W.
      2017 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 35th annual report.
      Although the 3208 resulting or related deaths were far fewer than the total referrals and interventions, concerns remain. Most reported exposures were due to a few classes of prescription medications (analgesics, sedative/hypnotics, antipsychotics, antidepressants) or readily available cleaning or personal care products. Accidental exposures are the most common among children, while suicidal ingestions are predominant among adults. We can, undoubtedly, endeavor to make our therapies and conveniences less harmful.
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      References

        • Gummin D.D.
        • Mowry J.B.
        • Spyker D.A.
        • Brooks D.E.
        • Osterthaler K.M.
        • Banner W.
        2017 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 35th annual report.
        Clin Toxicol (Phila). 2018; 56: 1213-1415
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      2. Heron M. Deaths: Leading causes for 2017. Hyattsville, MD: US Department of Health and Human Services/Centers for Disease Control and Prevention/National Center for Health Statistics/National Vital Statistics System; Vol 68, No 6: June 24, 2019. https://www.cdc.gov/nchs/data/nvsr/nvsr68/nvsr68_06-508.pdf. Accessed November 9, 2019.

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        The EXTRIP (EXtracorporeal TReatments In Poisoning) workgroup: guideline methodology.
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